The Determination of Phenylbutazone in Food of Animal Origin Using the ACQUITY UPLC I-Class and Xevo TQ-S
نویسنده
چکیده
BAC kG rOu n d The recent findings of undeclared horsemeat in beef products in Europe has prompted an urgent requirement for industry and the regulatory authorities to analyze meat and meat products for the presence of horse tissue and residues of the nonsteroidal anti-inflammatory drug (NSAID), phenylbutazone (PBZ). Phenylbutazone is a veterinary medicine permitted in some EU Member States which is used for pain relief and to reduce inflammation in non-food producing animals (dogs and horses). However, it is not permitted to be used in the treatment of animals destined for the human food chain. Any presence of the substance in food of animal origin therefore results from the illegal use of carcasses of treated horses. Low detection limits can be achieved using this ultra-sensitive UPLC-MS/MS method to ensure the detection of contaminated products. The Determination of Phenylbutazone in Food of Animal Origin Using the ACQUITY UPLC I-Class and Xevo TQ-S
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